@Article{info:doi/10.2196/cardio.9894,
author="Treskes, Roderick Willem
and Maan, Arie C
and Verwey, Harriette Florence
and Schot, Robert
and Beeres, Saskia Lambertha Maria Anna
and Tops, Laurens F
and Van Der Velde, Enno Tjeerd
and Schalij, Martin Jan
and Slats, Annelies Margaretha",
title="Mobile Health for Central Sleep Apnea Screening Among Patients With Stable Heart Failure: Single-Cohort, Open, Prospective Trial",
journal="JMIR Cardio",
year="2019",
month="Mar",
day="19",
volume="3",
number="1",
pages="e9894",
keywords="mobile health; central sleep apnea; heart failure; prevention; screening; mobile phone",
abstract="Background: Polysomnography is the gold standard for detection of central sleep apnea in patients with stable heart failure. However, this procedure is costly, time consuming, and a burden to the patient and therefore unsuitable as a screening method. An electronic health (eHealth) app to measure overnight oximetry may be an acceptable screening alternative, as it can be automatically analyzed and is less burdensome to patients. Objective: This study aimed to assess whether overnight pulse oximetry using a smartphone-compatible oximeter can be used to detect central sleep apnea in a population with stable heart failure. Methods: A total of 26 patients with stable heart failure underwent one night of both a polygraph examination and overnight saturation using a smartphone-compatible oximeter. The primary endpoint was agreement between the oxygen desaturation index (ODI) above or below 15 on the smartphone-compatible oximeter and the diagnosis of the polygraph. Results: The median age of patients was 66.4 (interquartile range, 62-71) years and 92{\%} were men. The median body mass index was 27.1 (interquartile range, 24.4-30.8) kg/m2. Two patients were excluded due to incomplete data, and two other patients were excluded because they could not use a smartphone. Seven patients had central sleep apnea, and 6 patients had obstructive sleep apnea. Of the 7 (of 22, 32{\%}) patients with central sleep apnea that were included in the analysis, 3 (13{\%}) had an ODI≥15. Of all patients without central sleep apnea, 8 (36{\%}) had an ODI<15. The McNemar test yielded a P value of .55. Conclusions: Oxygen desaturation measured by this smartphone-compatible oximeter is a weak predictor of central sleep apnea in patients with stable heart failure. ",
issn="2561-1011",
doi="10.2196/cardio.9894",
url="http://cardio.jmir.org/2019/1/e9894/",
url="https://doi.org/10.2196/cardio.9894",
url="http://www.ncbi.nlm.nih.gov/pubmed/31758786"
}