%0 Journal Article
%@ 2561-1011
%I JMIR Publications
%V 3
%N 1
%P e9894
%T Mobile Health for Central Sleep Apnea Screening Among Patients With Stable Heart Failure: Single-Cohort, Open, Prospective Trial
%A Treskes,Roderick Willem
%A Maan,Arie C
%A Verwey,Harriette Florence
%A Schot,Robert
%A Beeres,Saskia Lambertha Maria Anna
%A Tops,Laurens F
%A Van Der Velde,Enno Tjeerd
%A Schalij,Martin Jan
%A Slats,Annelies Margaretha
%+ Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands, 31 0715262020, r.w.treskes@lumc.nl
%K mobile health
%K central sleep apnea
%K heart failure
%K prevention
%K screening
%K mobile phone
%D 2019
%7 19.03.2019
%9 Original Paper
%J JMIR Cardio
%G English
%X Background: Polysomnography is the gold standard for detection of central sleep apnea in patients with stable heart failure. However, this procedure is costly, time consuming, and a burden to the patient and therefore unsuitable as a screening method. An electronic health (eHealth) app to measure overnight oximetry may be an acceptable screening alternative, as it can be automatically analyzed and is less burdensome to patients. Objective: This study aimed to assess whether overnight pulse oximetry using a smartphone-compatible oximeter can be used to detect central sleep apnea in a population with stable heart failure. Methods: A total of 26 patients with stable heart failure underwent one night of both a polygraph examination and overnight saturation using a smartphone-compatible oximeter. The primary endpoint was agreement between the oxygen desaturation index (ODI) above or below 15 on the smartphone-compatible oximeter and the diagnosis of the polygraph. Results: The median age of patients was 66.4 (interquartile range, 62-71) years and 92% were men. The median body mass index was 27.1 (interquartile range, 24.4-30.8) kg/m2. Two patients were excluded due to incomplete data, and two other patients were excluded because they could not use a smartphone. Seven patients had central sleep apnea, and 6 patients had obstructive sleep apnea. Of the 7 (of 22, 32%) patients with central sleep apnea that were included in the analysis, 3 (13%) had an ODI≥15. Of all patients without central sleep apnea, 8 (36%) had an ODI<15. The McNemar test yielded a P value of .55. Conclusions: Oxygen desaturation measured by this smartphone-compatible oximeter is a weak predictor of central sleep apnea in patients with stable heart failure. 
%M 31758786
%R 10.2196/cardio.9894
%U http://cardio.jmir.org/2019/1/e9894/
%U https://doi.org/10.2196/cardio.9894
%U http://www.ncbi.nlm.nih.gov/pubmed/31758786