TY  - JOUR
AU  - Treskes, Roderick Willem
AU  - Maan, Arie C
AU  - Verwey, Harriette Florence
AU  - Schot, Robert
AU  - Beeres, Saskia Lambertha Maria Anna
AU  - Tops, Laurens F
AU  - Van Der Velde, Enno Tjeerd
AU  - Schalij, Martin Jan
AU  - Slats, Annelies Margaretha
PY  - 2019
DA  - 2019/03/19
TI  - Mobile Health for Central Sleep Apnea Screening Among Patients With Stable Heart Failure: Single-Cohort, Open, Prospective Trial
JO  - JMIR Cardio
SP  - e9894
VL  - 3
IS  - 1
KW  - mobile health
KW  - central sleep apnea
KW  - heart failure
KW  - prevention
KW  - screening
KW  - mobile phone
AB  - Background: Polysomnography is the gold standard for detection of central sleep apnea in patients with stable heart failure. However, this procedure is costly, time consuming, and a burden to the patient and therefore unsuitable as a screening method. An electronic health (eHealth) app to measure overnight oximetry may be an acceptable screening alternative, as it can be automatically analyzed and is less burdensome to patients. Objective: This study aimed to assess whether overnight pulse oximetry using a smartphone-compatible oximeter can be used to detect central sleep apnea in a population with stable heart failure. Methods: A total of 26 patients with stable heart failure underwent one night of both a polygraph examination and overnight saturation using a smartphone-compatible oximeter. The primary endpoint was agreement between the oxygen desaturation index (ODI) above or below 15 on the smartphone-compatible oximeter and the diagnosis of the polygraph. Results: The median age of patients was 66.4 (interquartile range, 62-71) years and 92% were men. The median body mass index was 27.1 (interquartile range, 24.4-30.8) kg/m2. Two patients were excluded due to incomplete data, and two other patients were excluded because they could not use a smartphone. Seven patients had central sleep apnea, and 6 patients had obstructive sleep apnea. Of the 7 (of 22, 32%) patients with central sleep apnea that were included in the analysis, 3 (13%) had an ODI≥15. Of all patients without central sleep apnea, 8 (36%) had an ODI<15. The McNemar test yielded a P value of .55. Conclusions: Oxygen desaturation measured by this smartphone-compatible oximeter is a weak predictor of central sleep apnea in patients with stable heart failure. 
SN  - 2561-1011
UR  - http://cardio.jmir.org/2019/1/e9894/
UR  - https://doi.org/10.2196/cardio.9894
DO  - 10.2196/cardio.9894
ID  - info:doi/10.2196/cardio.9894
ER  -