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Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Given the anticipated overlap of these conditions, ≈20% (n=90) of women will have at least one maternal metabolic disease of interest (secondary outcome). Study data are collected using paper case report forms. These paper documents will be kept in a locked cupboard accessible only to local research staff. Patient information is collected and stored by the investigators in a confidential REDCap (Research Electronic Data Capture system; Vanderbilt University), with password protection and restricted access.

Sarah A L Price, Digsu N Koye, Alice Lewin, Alison Nankervis, Stefan C Kane

JMIR Res Protoc 2025;14:e72542

Using Large Language Models to Automate Data Extraction From Surgical Pathology Reports: Retrospective Cohort Study

Using Large Language Models to Automate Data Extraction From Surgical Pathology Reports: Retrospective Cohort Study

We reviewed 102 surgical pathology reports from 102 patients and excluded reports if they were from other organ sites (n=10), benign (n=2), cytopathology (n=5), or outside review (n=1). We included 84 reports for analysis. The study flowchart is shown in Figure 2. Flowchart of the study design and analysis. *The concordance rate was calculated as the total number of concordant answers/total number of answers for each of the 12 medical question answering (MQA).

Denise Lee, Akhil Vaid, Kartikeya M Menon, Robert Freeman, David S Matteson, Michael L Marin, Girish N Nadkarni

JMIR Form Res 2025;9:e64544

Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map

Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map

A much smaller number of studies (n=6) examined the utility of VR in chronic pain populations including intensive pain rehabilitation (n=1) [112], chronic burn dressing (n=1) [113], chronic musculoskeletal pain (n=1) [114], chronic cancer-related pain (n=2) [115,116], and chronic abdominal pain (n=1) [117]. See Figure 2 for the summary of pain populations included across the studies.

Courtney W Hess, Brittany N Rosenbloom, Giulia Mesaroli, Cristal Lopez, Nhat Ngo, Estreya Cohen, Carley Ouellette, Jeffrey I Gold, Deirdre Logan, Laura E Simons, Jennifer N Stinson

JMIR Pediatr Parent 2025;8:e63854

Changes in Physical Activity, Heart Rate, and Sleep Measured by Activity Trackers During the COVID-19 Pandemic Across 34 Countries: Retrospective Analysis

Changes in Physical Activity, Heart Rate, and Sleep Measured by Activity Trackers During the COVID-19 Pandemic Across 34 Countries: Retrospective Analysis

The proportion of sedentary individuals increased from 38% (n=14,177) in 2019 to 52% (n=19,510) in 2020 and remained elevated at 51% (n=18,972) in 2022, while the proportion of active individuals dropped from 8% (n=2857) to 6% (n=2352) in 2020 before returning to 8% (n=2877) in 2022 (Figure 4). Figure 4 illustrates shifts in activity levels throughout the study period.

Bastien Wyatt, Nicolas Forstmann, Nolwenn Badier, Anne-Sophie Hamy, Quentin De Larochelambert, Juliana Antero, Arthur Danino, Vincent Vercamer, Paul De Villele, Benjamin Vittrant, Thomas Lanz, Fabien Reyal, Jean-François Toussaint, Lidia Delrieu

J Med Internet Res 2025;27:e68199

Perspectives of Adolescents and Young Adults With Inflammatory Bowel Disease on a Biopsychosocial Transition Intervention: Qualitative Interview Study

Perspectives of Adolescents and Young Adults With Inflammatory Bowel Disease on a Biopsychosocial Transition Intervention: Qualitative Interview Study

Participant characteristics (N=21). a Response categories based on participants’ language. b Multiple response options were possible. c IBDU: inflammatory bowel disease type unclassified. d UC: ulcerative colitis. e IBD: inflammatory bowel disease. Adolescents and young adults expressed a range of reflections on the meaning of the transition from pediatric to adult health care.

Brooke Allemang, Ashleigh Miatello, Mira Browne, Melanie Barwick, Pranshu Maini, Joshua Eszczuk, Chetan Pandit, Tandeep Sadhra, Laura Forhan, Natasha Bollegala, Nancy Fu, Kate Lee, Emily Dekker, Irina Nistor, Sara Ahola Kohut, Laurie Keefer, Anne Marie Griffiths, Thomas D Walters, Samantha Micsinszki, David R Mack, Sally Lawrence, Karen I Kroeker, Jacqueline de Guzman, Aalia Tausif, Claudia Tersigni, Samantha J Anthony, Eric I Benchimol

JMIR Pediatr Parent 2025;8:e64618

Evaluation of the Tu’Washindi Na PrEP Intervention to Reduce Gender-Based Violence and Increase Preexposure Prophylaxis Uptake and Adherence Among Kenyan Adolescent Girls and Young Women: Protocol for a Cluster Randomized Controlled Trial

Evaluation of the Tu’Washindi Na PrEP Intervention to Reduce Gender-Based Violence and Increase Preexposure Prophylaxis Uptake and Adherence Among Kenyan Adolescent Girls and Young Women: Protocol for a Cluster Randomized Controlled Trial

We have randomized 22 administrative wards in a 1:1 ratio and aim to enroll about 72 adolescent girls and young women from each (total N=about 1584) to receive either the Tu’Washindi intervention plus usual HIV prevention services, or usual HIV prevention services alone.

Sarah T Roberts, Alexandra M Minnis, Sue Napierala, Elizabeth T Montgomery, Lina Digolo, Mackenzie L Cottrell, Erica N Browne, Jacqueline Ndirangu, Joyce Boke, Kawango Agot

JMIR Res Protoc 2025;14:e55931

Considering Theory-Based Gamification in the Co-Design and Development of a Virtual Reality Cognitive Remediation Intervention for Depression (bWell-D): Mixed Methods Study

Considering Theory-Based Gamification in the Co-Design and Development of a Virtual Reality Cognitive Remediation Intervention for Depression (bWell-D): Mixed Methods Study

Briefly, participants comprising individuals with lived experience of depression (n=15) and clinicians (n=12) were interviewed, and the results were transcribed and coded followed by thematic analysis. The demographic and clinical characteristics of these end users are described in our previous paper.

Mark Hewko, Vincent Gagnon Shaigetz, Michael S Smith, Elicia Kohlenberg, Pooria Ahmadi, Maria Elena Hernandez Hernandez, Catherine Proulx, Anne Cabral, Melanie Segado, Trisha Chakrabarty, Nusrat Choudhury

JMIR Serious Games 2025;13:e59514

Perspectives on and Experiences With Remote Monitoring and Patient-Initiated Care Among Norwegian Patients With Axial Spondyloarthritis: Qualitative Study

Perspectives on and Experiences With Remote Monitoring and Patient-Initiated Care Among Norwegian Patients With Axial Spondyloarthritis: Qualitative Study

Of 346 screened patients, 243 were enrolled between September 2021 and June 2022 and randomly allocated 1:1:1 to either usual care (n=82), remote monitoring (n=80), or patient-initiated care (n=81). Usual care entails adherence to the current conventional follow-up regimen, involving patient-reported outcome measures (PROMs), blood tests, and hospital visits every 6 months with an experienced rheumatology nurse or rheumatologist.

Christine Hillestad Hestevik, Cecilie Varsi, Nina Østerås, Anne Therese Tveter, Jon Skandsen, Hedda Eik

J Med Internet Res 2025;27:e63569