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Patient-Centered Risk Prediction, Prevention, and Intervention Platform (TIMELY) to Support the Continuum of Care in Coronary Artery Disease Using eHealth and Artificial Intelligence: Protocol for a Randomized Controlled Trial

Patient-Centered Risk Prediction, Prevention, and Intervention Platform (TIMELY) to Support the Continuum of Care in Coronary Artery Disease Using eHealth and Artificial Intelligence: Protocol for a Randomized Controlled Trial

Such an approach should include both a continuous risk analysis by monitoring multiple disease-related prognostic parameters as well as regular support and guidance for a cardiac healthy lifestyle. A recent meta-analysis by Heimer et al [16] demonstrated that e Health-based, phase-3 CR is effective in increasing exercise capacity, improving quality of life, and decreasing blood pressure (BP).

Mirela Habibovic, Emma Douma, Hendrik Schäfer, Manuela Sestayo-Fernandez, Tom Roovers, Xin Sun, Henrik Schmidt, Mona Kotewitsch, Jos Widdershoven, David Cantarero-Prieto, Frank Mooren, Carlos Pena-Gil, José Rámon González Juanatey, Martin Schmidt, Hagen Malberg, Vassilis Tsakanikas, Dimitrios Fotiadis, Dimitris Gatsios, Jos Bosch, Willem Johan Kop, Boris Schmitz

JMIR Res Protoc 2025;14:e66283

Improving Data Integrity in Samples Obtained From Web-Based Recruitment: Protocol for the Development of a Novel System for Assessing Participant Authenticity in a Remote Longitudinal Cohort Study of Polysubstance Use

Improving Data Integrity in Samples Obtained From Web-Based Recruitment: Protocol for the Development of a Novel System for Assessing Participant Authenticity in a Remote Longitudinal Cohort Study of Polysubstance Use

In this paper, we outline a novel system for authenticating participants recruited remotely via a third-party recruitment company for a longitudinal cohort study examining trajectories of opioid-involved PSU and other health outcomes.

Chavez R Rodriguez, Maya Campbell, Erin E Bonar, Jason E Goldstick, Maureen A Walton, Lewei A Lin, Lara N Coughlin

JMIR Res Protoc 2025;14:e69956

Examining Potential Implicit Bias in Oncologist-Patient Communication (CONNECT): Protocol for an Observational 2-Site Study

Examining Potential Implicit Bias in Oncologist-Patient Communication (CONNECT): Protocol for an Observational 2-Site Study

Compared with White patients, minoritized patients (Black and Hispanic patients) have a higher incidence of advanced solid cancer and have a higher mortality rate [1,2]. Although many factors contribute to such disparities, physician implicit bias may be a contributing factor [3]. Moreover, disparities have been reported in the outcomes of minoritized patients with advanced solid cancer [4,5]. Rather than improving over time, these inequities have been widening [6].

Veronica C K Duck, Marsha L Augustin, Jose A Morillo, Aviel N Alkon, Robert M Thomas, Brianna N Richardson, Lihua Li, Kathryn I Pollak, Cardinale B Smith

JMIR Res Protoc 2025;14:e66086

Classification of Individuals With COVID-19 and Post–COVID-19 Condition and Healthy Controls Using Heart Rate Variability: Machine Learning Study With a Near–Real-Time Monitoring Component

Classification of Individuals With COVID-19 and Post–COVID-19 Condition and Healthy Controls Using Heart Rate Variability: Machine Learning Study With a Near–Real-Time Monitoring Component

A recent systematic review and meta-analysis further supports the feasibility of using wearable-derived HRV data to detect and monitor COVID-19 [45]. Beyond its utility as a biomarker of SARS-Co V-2 infection, there is evidence suggesting that persistent HRV alterations following SARS-Co V-2 infection may serve as a valuable marker for what is commonly known as post–COVID-19 condition.

Carlos Alberto Sanches, Andre Felipe Henriques Librantz, Luciana Maria Malosá Sampaio, Peterson Adriano Belan

J Med Internet Res 2025;27:e76613

Assessment of Two Online Interventions for Veterans With Chronic Pain: Protocol for a Randomized Controlled Efficacy Trial

Assessment of Two Online Interventions for Veterans With Chronic Pain: Protocol for a Randomized Controlled Efficacy Trial

This study aims to conduct a 3-site, randomized controlled, parallel group efficacy trial of VACT-CP (n=120) versus an active online control condition (Online Pain School; n=80) with a 1:2 allocation ratio (Online Pain School vs VACT-CP arms) to allow mediation analysis of hypothesis 3 in the VACT-CP group only. Online Pain School is adapted from a common in-person treatment option for veterans, modified for an online format, and delivered through a VA-approved, secure website.

Erin D Reilly, Hannah L Grigorian, Alicia A Heapy, Bella Etingen, Megan M Kelly, Noah R Wolkowicz, Caitlin M Girouard, Timothy P Hogan, Katarina Bernice, Timothy Bickmore

JMIR Res Protoc 2025;14:e70601

Identifying Substance Use and High-Risk Sexual Behavior Among Sexual and Gender Minority Youth by Using Mobile Phone Data: Development and Validation Study

Identifying Substance Use and High-Risk Sexual Behavior Among Sexual and Gender Minority Youth by Using Mobile Phone Data: Development and Validation Study

used a dating app to meet sexual and substance use partners in the past 3 months, (9) own a smartphone, (10) reside in the United States, (11) be willing to participate in a 12-month study, and (12) be able to provide informed consent.

Mehrab Beikzadeh, Ian W Holloway, Kimmo Kärkkäinen, Chenglin Hong, Cory Cascalheira, Elizabeth S C Wu, Callisto Boka, Alexandra C Avendaño, Elizabeth A Yonko, Majid Sarrafzadeh

Online J Public Health Inform 2025;17:e68013

Frequency and Predictors of Virtual Visits in Patients With Heart Failure Within a Large Health System: Retrospective Cohort Study

Frequency and Predictors of Virtual Visits in Patients With Heart Failure Within a Large Health System: Retrospective Cohort Study

This was a retrospective cohort study conducted at the UCHealth health system, which is a large regional health system in Colorado and areas of Wyoming and Nebraska. UCHealth is comprised of 14 hospitals, 900 clinics, and over 6000 physicians who serve academic, rural, suburban, and community settings. The entire system is serviced by a single instance of the Epic EHR software program (Epic Systems, Verona, WI, United States).

Anna M Maw, Garth C Wright, Meagan R Bean, Larry A Allen, Daniel D Matlock, Lilia Cervantes, Russell E Glasgow, Amy G Huebschmann, Kathryn L Colborn, Thomas K Houston, Katie E Trinkley

J Med Internet Res 2025;27:e70414

Staff Enablement of the Tovertafel for Enrichment in Residential Aged Care: Field Study

Staff Enablement of the Tovertafel for Enrichment in Residential Aged Care: Field Study

The staff participants signed a participant information sheet and consent form (PICF) and received an Aus $20 (US $13.37) gift voucher as a token of appreciation. The care home residents who participated in the interviews were provided with a PICF that included pictures of Tovertafel games, along with a textual description of the technology. Some of these residents were shown a You Tube video of the Tovertafel if they were unable to understand its functionality from the PICF alone.

Ryan M Kelly, Asmita Manchha, Jenny Waycott, Rajna Ogrin, Judy A Lowthian

JMIR Aging 2025;8:e67919

Adoption of Personal Health Records in Dutch Hospitals and Private Medical Clinics: Longitudinal Study

Adoption of Personal Health Records in Dutch Hospitals and Private Medical Clinics: Longitudinal Study

Thus, a PHE combines the electronic and personal health records (EHR + PHR) in a single portal allowing patients to access their medical data from various health care organizations, record their own medical data, and control access to their medical data. This description of a PHE largely overlaps with the definition of PHR.

Doris van der Smissen, Christine Leenen-Brinkhuis, Kim M E Janssens, Petra J Porte, Marcel A L M van Assen, Anne Marie Weggelaar-Jansen

J Med Internet Res 2025;27:e71915

Pocket Parent-Child Interaction Therapy (PCIT) Online for Young Children With Disruptive Behaviors: Open Trial

Pocket Parent-Child Interaction Therapy (PCIT) Online for Young Children With Disruptive Behaviors: Open Trial

Given the need for a more holistic evaluation of m Health BPT, this study aimed to examine an m Health version of PCIT through the aspects of the RE-AIM framework lens. Building on the success of a PCIT-related multimedia book [47], the content was adapted and expanded into a web-based platform. Pocket PCIT Online is a brief, self-directed web-based adaptation of Parent-Child Interaction Therapy, developed to increase accessibility of evidence-based parenting strategies [14,48-50].

Jason F Jent, Megan Golson, Abigail Peskin, William A Rothenberg, Hanan Salem, Allison Weinstein, Eileen Davis, Meaghan Parlade, Jocelyn Stokes, Tasha Brown, Michelle Berkovits, Dainelys Garcia

J Med Internet Res 2025;27:e69887