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Evaluating the Acceptability and Utility of a Personalized Wellness App (Aspire2B) Using AI-Enabled Digital Biomarkers: Engagement Enhancement Pilot Study

Evaluating the Acceptability and Utility of a Personalized Wellness App (Aspire2B) Using AI-Enabled Digital Biomarkers: Engagement Enhancement Pilot Study

At onboarding, participants in each challenge (nutrition, movement, and sleep) were similar regarding height, weight, and BMI, but were statistically different in terms of age, such that those in the sleep challenge had significantly lower chronological age (P=.02). Demographics for participants who downloaded the Aspire2 B app. Participant ages have been grouped in this table for clarity and ease of interpretation, but they are not grouped in the analyses.

Calissa J Leslie-Miller, Shellen R Goltz, Pamela L Barrios, Christopher C Cushing, Teena Badshah, Corey T Ungaro, Shankang Qu, Yulia Berezhnaya, Tristin D Brisbois

JMIR Form Res 2025;9:e63471

SEARCH Study: Text Messages and Automated Phone Reminders for HPV Vaccination in Uganda: Randomized Controlled Trial

SEARCH Study: Text Messages and Automated Phone Reminders for HPV Vaccination in Uganda: Randomized Controlled Trial

There was no significant difference in requested mode based on HPV vaccine dose or language (desired text messages for initiation reminders (22/39, 56%), versus for completion reminders (26/39, 67%; P=.35), desired text messages for reminders in English (21/28, 75%) versus in Luganda (27/50, 54%; P=.07). Enrollment flow diagram. Characteristics of study participants. a HPV: human papillomavirus. b KCCA: Kampala Capital City Authority.

Sabrina B Kitaka, Joseph Rujumba, Sarah K Zalwango, Betsy Pfeffer, Lubega Kizza, Juliane P Nattimba, Ashley B Stephens, Nicolette Nabukeera-Barungi, Chelsea S Wynn, Juliet N Babirye, John Mukisa, Ezekiel Mupere, Melissa S Stockwell

JMIR Mhealth Uhealth 2025;13:e63527

Improving Diet Quality of People Living With Obesity by Building Effective Dietetic Service Delivery Using Technology in a Primary Health Care Setting: Protocol for a Randomized Controlled Trial

Improving Diet Quality of People Living With Obesity by Building Effective Dietetic Service Delivery Using Technology in a Primary Health Care Setting: Protocol for a Randomized Controlled Trial

P values A sample size of 342 participants (n=171 per group) will have 90% power to detect a difference in change between arms of at least 5% of body weight at 12 months between groups, using a conservative estimate of SD, at 90% power and 5% level of significance. Assuming 20% (n=86) of participants are not followed up, this would necessitate 430 (215 in each group) participants to be recruited.

Deborah A Kerr, Clare E Collins, Andrea Begley, Barbara Mullan, Satvinder S Dhaliwal, Claire E Pulker, Fengqing Zhu, Marie Fialkowski, Richard L Prince, Richard Norman, Anthony P James, Paul Aveyard, Helen Mitchell, Jacquie Garton-Smith, Megan E Rollo, Chloe Maxwell-Smith, Amira Hassan, Hayley Breare, Lucy M Butcher, Christina M Pollard

JMIR Res Protoc 2025;14:e64735

Effect of a Digital Health Exercise Program on the Intention for Spinal Surgery in Adult Spinal Deformity: Exploratory Cross-Sectional Survey

Effect of a Digital Health Exercise Program on the Intention for Spinal Surgery in Adult Spinal Deformity: Exploratory Cross-Sectional Survey

The mean (SD) intent for surgery scores before compared to after SRT were 1.29 (0.53) and 1.14 (0.35), respectively (mean difference 0.15 [P=.006]; Table 3). Participants with “No Intent” for spinal surgery pre- versus postuse of SRT (42/56 versus 48/56, respectively) corresponded to an absolute risk reduction of 11% and a number needed to treat of 9 to potentially avert 1 spinal fusion (1 divided by 0.11).

Marsalis Christian Brown, Christopher Quincy Lin, Christopher Jin, Matthew Rohde, Brett Rocos, Jonathan Belding, Barrett I Woods, Stacey J Ackerman

JMIR Form Res 2025;9:e66889