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PA measurement reactivity has been observed in a subset of studies to date [25,29-31], and some PA researchers consider reactivity a critical source of bias that warrants increased attention and mitigating actions, such as requiring extra days of observation to get used to the PA monitor or removing the first 1-2 days of PA observation from analyses [30].
JMIR Res Protoc 2025;14:e67438
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The enrollment visit consisted of an informed consent process, a computer-assisted self-interview behavioral survey, HIV and STI testing, training on using the study app, and a counseling session to include pre- and posttest HIV prevention information and a discussion about Pr EP and STI PEP options. Participants who completed an enrollment visit were compensated US $125 regardless of whether they subsequently participated in the study.
JMIR Res Protoc 2025;14:e56096
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Given the complexity and individualized needs of the postpartum patient we postulated that a conversational agent using NLP might be a good solution and be acceptable to this population. We envisioned a 24/7 available SMS text message—based support program that interpreted patients’ postpartum concerns, responded in real sentences and could also alert clinicians in real time when appropriate.
JMIR AI 2025;4:e58454
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Using a user experience technique traditionally referred to as a cognitive walk-through, we aimed to explore participants’ emotional responses as they engaged with the interface [84,85]. We adapted a walk-through user testing methodology [86] and created a 6-page emotional walk-through booklet (Figure 3) that was distributed to participants along with a link to a prototype of the web-based mental health screening platform intended for national deployment in the near future.
JMIR Pediatr Parent 2025;8:e65163
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The Fire Fighter Cancer Cohort Study: Protocol for a Longitudinal Occupational Cohort Study
Firefighter liaisons serve a critical role in community collaboration and are vital to the success of the study. At least 1 liaison is onboarded to the IRB-approved protocol following the completion of a shortened human participants training course and receipt of a signed permission form from the department.
JMIR Res Protoc 2025;14:e70522
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A SMART is a type of factorial design used to develop and optimize adaptive interventions by studying treatments in a sequential manner [17-19]. In a SMART, participants can receive multiple interventions over time depending on their response to previous treatments and may be randomized more than once. For example, if a participant does not sufficiently respond to an initial course of care that they were initially randomized to receive, they might be rerandomized to one of several second-line treatments.
JMIR Res Protoc 2025;14:e68441
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Therefore, we argue that this method, in combination with a community detection algorithm, allows for a more novel approach to answering the question of how EF tasks group together to form constructs.
Adaptive Cognitive Evaluation-Explorer (ACE-X) is a research tool developed at Neuroscape, a center in the Department of Neurology at the University of California, San Francisco, to assess the 3 facets of cognitive control (attention, working memory, and cognitive flexibility) [16,17].
J Med Internet Res 2025;27:e60041
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Over the past decade, the internet has evolved into a primary source of knowledge for many individuals. The demand for purchasing things online, including medications, has experienced a parallel surge [1]. In the last few years, a discernible transformation has occurred within the pharmacy industry, whereby a considerable number of conventional pharmacies have adopted e-commerce platforms.
JMIR Mhealth Uhealth 2025;13:e59884
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Consumer-Grade Neurofeedback With Mindfulness Meditation: Meta-Analysis
This has led to a proliferation of technology supported mindfulness [8-13]. Neurofeedback may be one method of supporting or enhancing mindfulness learning [12,32,33]. Neurofeedback consists of measuring brain signals during a task and relaying those signals (targets) to the participant. The participant may learn with repeated practice to modulate the target, with beneficial outcomes.
J Med Internet Res 2025;27:e68204
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We do this in the context of a GPT-4–based VSP that we developed for a medical simulation study. The learner, taking on the role of a primary care physician (PCP), simulates a phone call with the VSP to discuss an abnormal screening mammogram result that requires a patient to schedule a biopsy.
JMIR Form Res 2025;9:e65670
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