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Optimizing Cardiovascular Risk Management in Primary Care Using a Personalized eCoach Solution Enhanced by an Artificial Intelligence–Driven Clinical Prediction Model: Protocol from the Coronary Artery Disease Risk Estimation and Early Detection Consortium

A paired sample t test will be performed for at least the 10-year ASCVD risk, assuming normality. Individual components, including systolic blood pressure, use of blood pressure medication, total cholesterol, HDL, use of lipid-modifying agents, smoking status, and moderate to vigorous physical activity, will be evaluated using the Mc Nemar test for dichotomous outcomes and the paired sample t test for continuous variables.

Rutger van Mierlo, Bart Scheenstra, Joost Verbeek, Anke Bruninx, Petros Kalendralis, Inigo Bermejo, Andre Dekker, Arnoud van 't Hof, Marieke Spreeuwenberg, Laura Hochstenbach