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Baseline Smartphone App Survey Return in the Electronic Framingham Heart Study Offspring and Omni 1 Study: eCohort Study

We performed all analyses with RStudio in R (version 4.3.1; R Foundation) for Windows and considered 2-sided P The Offspring examination 10 and Omni examination 5 and the e FHS protocols were reviewed and approved by the Institutional Review Board at Boston University Medical Center (protocol numbers H-32132, H-36586, and H-40737). i Phone users were allowed to choose to use a study Apple Watch. No compensation was given to participants. Data were anonymized for analysis.

Jian Rong, Chathurangi H Pathiravasan, Yuankai Zhang, Jamie M Faro, Xuzhi Wang, Eric Schramm, Belinda Borrelli, Emelia J Benjamin, Chunyu Liu, Joanne M Murabito

JMIR Aging 2024;8:e64636

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Agreement Between Apple Watch and Actical Step Counts in a Community Setting: Cross-Sectional Investigation From the Framingham Heart Study

All participants provided written informed consent and the institutional review board at Boston University Medical Center approved the study protocols (H-32132). During the 8-day wear period, participants were asked to remove the Actical accelerometer (Philips Respironics, model numbers 198-0302-xx, Respironics Co Inc) each night for sleep and when bathing or swimming. Actical data were recorded in 30-second epochs and expressed as counts (or steps) per 30 seconds.

Nicole L Spartano, Yuankai Zhang, Chunyu Liu, Ariel Chernofsky, Honghuang Lin, Ludovic Trinquart, Belinda Borrelli, Chathurangi H Pathiravasan, Vik Kheterpal, Christopher Nowak, Ramachandran S Vasan, Emelia J Benjamin, David D McManus, Joanne M Murabito

JMIR Biomed Eng 2024;9:e54631

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Association of Smartwatch-Based Heart Rate and Physical Activity With Cardiorespiratory Fitness Measures in the Community: Cohort Study

The Boston University Medical Campus institutional review board reviewed and approved the study (H-36586 and H-32132). All participants provided informed consent for their participation in e FHS and for participation in examination 3, which included the CPET. Data were deidentified for analysis. Participants were not compensated for participating in the study. The CPET protocol used in FHS has been described previously [7,21,22] and is briefly summarized through the subsequent procedures.

Yuankai Zhang, Xuzhi Wang, Chathurangi H Pathiravasan, Nicole L Spartano, Honghuang Lin, Belinda Borrelli, Emelia J Benjamin, David D McManus, Martin G Larson, Ramachandran S Vasan, Ravi V Shah, Gregory D Lewis, Chunyu Liu, Joanne M Murabito, Matthew Nayor

J Med Internet Res 2024;26:e56676

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Association of Arterial Stiffness With Mid- to Long-Term Home Blood Pressure Variability in the Electronic Framingham Heart Study: Cohort Study

The e FHS and FHS protocols were approved by the institutional review board at the Boston University Medical Center (H-36586 and H-32132). We confirm that we have the permission to use the data. Characteristics of the study sample are summarized in Table 1. Our study sample consisted of 857 participants who were middle-aged on average, with a moderate prevalence of hypertension.

Xuzhi Wang, Yuankai Zhang, Chathurangi H Pathiravasan, Nene C Ukonu, Jian Rong, Emelia J Benjamin, David D McManus, Martin G Larson, Ramachandran S Vasan, Naomi M Hamburg, Joanne M Murabito, Chunyu Liu, Gary F Mitchell

JMIR Cardio 2024;8:e54801

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Association of Depressive Symptom Trajectory With Physical Activity Collected by mHealth Devices in the Electronic Framingham Heart Study: Cohort Study

The protocols for e FHS and the FHS were approved by the Institutional Review Board (H-36586 and H-32132) at the Boston University Medical Center. We selected participants from Gen 3, OMNI2, and NOS cohorts who participated in all 3 FHS exams. Trained technicians administered the 20-item Center for Epidemiological Studies-Depression (CES-D) scale at each of the 3 research exams.

Xuzhi Wang, Chathurangi H Pathiravasan, Yuankai Zhang, Ludovic Trinquart, Belinda Borrelli, Nicole L Spartano, Honghuang Lin, Christopher Nowak, Vik Kheterpal, Emelia J Benjamin, David D McManus, Joanne M Murabito, Chunyu Liu

JMIR Ment Health 2023;10:e44529

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Step Count, Self-reported Physical Activity, and Predicted 5-Year Risk of Atrial Fibrillation: Cross-sectional Analysis

This study was approved by the Institutional Review Board of Boston University Medical Center (approval number: H-36586). All participants provided written informed consent. In this analysis, we selected e FHS participants, as displayed in Figure S1 in Multimedia Appendix 1. Of the 3521 participants examined in the research center, 1948 had a compatible i Phone, provided consent, and were ultimately enrolled in our e FHS sample. Only 1185 used the Apple Watch and returned step data.

Ayelet Shapira-Daniels, Jelena Kornej, Nicole L Spartano, Xuzhi Wang, Yuankai Zhang, Chathurangi H Pathiravasan, Chunyu Liu, Ludovic Trinquart, Belinda Borrelli, David D McManus, Joanne M Murabito, Emelia J Benjamin, Honghuang Lin

J Med Internet Res 2023;25:e43123

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Relations Between BMI Trajectories and Habitual Physical Activity Measured by a Smartwatch in the Electronic Cohort of the Framingham Heart Study: Cohort Study

The study protocol was approved by the Boston University Medical Center Institutional Review Board (H-36586 and H-32132). All participants provided informed consent. At each examination visit in the FHS research center, trained personnel routinely measured participant’s weight to the nearest pound and height to the nearest quarter-inch, using uniform measuring devices. BMI was calculated by dividing the participant’s weight in kilograms by the square of the height in meters (kg/m2).

Michael M Hammond, Yuankai Zhang, Chathurangi H. Pathiravasan, Honghuang Lin, Mayank Sardana, Ludovic Trinquart, Emelia J Benjamin, Belinda Borrelli, Emily S Manders, Kelsey Fusco, Jelena Kornej, Nicole L Spartano, Vik Kheterpal, Christopher Nowak, David D McManus, Chunyu Liu, Joanne M Murabito