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Coronary Computed Tomographic Angiography to Optimize the Diagnostic Yield of Invasive Angiography for Low-Risk Patients Screened With Artificial Intelligence: Protocol for the CarDIA-AI Randomized Controlled Trial

Coronary Computed Tomographic Angiography to Optimize the Diagnostic Yield of Invasive Angiography for Low-Risk Patients Screened With Artificial Intelligence: Protocol for the CarDIA-AI Randomized Controlled Trial

As such, we have deployed the AI model in our local cardiac center and conducted a pilot study using a silent trial design [16] to establish feasibility within the centralized triage pathway and address implementation issues (Schwalm et al, unpublished paper, April 2025). With the individual components of the intervention validated and piloted, the next appropriate step is to conduct a clinical trial of the intervention to measure its impact on clinical outcomes.

Jeremy Petch, Juan Pablo Tabja Bortesi, Tej Sheth, Madhu Natarajan, Natalia Pinilla-Echeverri, Shuang Di, Shrikant I Bangdiwala, Karen Mosleh, Omar Ibrahim, Kevin R Bainey, Julian Dobranowski, Maria P Becerra, Katie Sonier, Jon-David Schwalm

JMIR Res Protoc 2025;14:e71726

Length of Initial Prescription at Hospital Discharge and Long-Term Medication Adherence for Elderly, Post-Myocardial Infarction Patients: Protocol for an Interrupted Time Series Study

Length of Initial Prescription at Hospital Discharge and Long-Term Medication Adherence for Elderly, Post-Myocardial Infarction Patients: Protocol for an Interrupted Time Series Study

In a preliminary survey of 82 health care providers in the study region, 95% said they would use standardized discharge prescriptions with 3 months of cardiac medication supplies and 3 repeats but less than 50% admitted that they currently provide medication supplies to cover a year (Schwalm, unpublished data). Further education (eg, emails, mailouts, site visits) occurred every 3 months during the intervention period.

J D Schwalm, Noah M Ivers, Zachary Bouck, Monica Taljaard, Madhu K Natarajan, Lisa Dolovich, Kednapa Thavorn, Tara McCready, Erin O'Brien, Jeremy M Grimshaw

JMIR Res Protoc 2020;9(11):e18981