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Skip search results from other journals and go to results- 2 JMIR Research Protocols
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The FLI is a biomarker for noninvasive fat layer prediction of nonalcoholic fatty liver disease (NAFLD). It has been validated against imaging methods for fatty liver diagnosis in the United States, with an accuracy of 0.84 (95% CI 0.81-0.87) [14]. Also, the FLI was validated with an area under the curve value of 0.87 or 0.785 in the Korean population [20,21].
JMIR Public Health Surveill 2024;10:e57168
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We read with great interest the article by Kwon et al [1] in the Journal of Medical Internet Research that described an app for lifestyle coaching intervention for patients with nonalcoholic fatty liver disease (NAFLD). With the paradigm shift in medicine, we are delighted to find that the study took into account the importance of psychological and social factors for patients. Digital therapeutics have shown remarkable contributions in various fields [2].
J Med Internet Res 2024;26:e59208
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Nonalcoholic fatty liver disease (NAFLD) stands as the foremost chronic liver condition, impacting approximately 1.7 billion individuals worldwide. NAFLD manifests as a multifaceted chronic liver disorder marked by an excessive buildup of fat within liver tissue. As hepatic steatosis advances, it exacerbates the onset and progression of hepatitis and fibrosis, while heightening the likelihood of liver cancer.
JMIR Form Res 2024;8:e53654
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Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the world [1]. NAFLD is defined as >5% fat in the liver (steatosis) among people who drink moderate amounts or no alcohol and have no other chronic liver diseases [2]. NAFLD reflects a spectrum of liver pathologies, ranging from simple steatosis to a more severe condition called nonalcoholic steatohepatitis (NASH), which includes inflammation and potential scarring of the liver [3].
JMIR Cardio 2024;8:e52576
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NAFLD encompasses a spectrum of diseases including NAFL, which has a more benign course, and NASH, which can progress to cirrhosis and hepatocellular carcinoma (HCC) [6]. Due to the heterogeneous nature of the disease, the undetermined symptoms, and the high disease burden, there is increasing appreciation that NAFLD may also be becoming an important cause of HCC [7]. The reported global prevalence of NAFLD and HCC varies between 2% and 58.5% [8].
Interact J Med Res 2023;12:e40653
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Thus, to investigate the utility and cost-benefit of adding mp MRI into the care pathway of those with suspected NAFLD in Europe (European Union territories and United Kingdom [UK]), this randomized, multi-center, phase 4 control trial to investigate the use of mp MRI as a standardized diagnostic test for NAFLD/NASH was designed.
JMIR Res Protoc 2020;9(10):e19189
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This was part of the routine clinical service offered to overweight or obese NAFLD patients seen at the NAFLD clinic.
All outcomes were part of routine measurements taken by trained nurses and blood tests conducted at the outpatient NAFLD clinic. Assessors were not blinded to the groups allocated to the study participants. Body weight was measured using a calibrated digital weighing machine (Seca 767, Germany) to the nearest 0.1 kg.
JMIR Mhealth Uhealth 2020;8(4):e14802
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Obesity-associated diseases, such as type 2 diabetes mellitus (T2 DM) and nonalcoholic fatty liver disease (NAFLD), are major public health issues worldwide, affecting more than 6% and 25% of the world population, respectively [1,2]. The influence of gut bacteria on the development of obesity and metabolic syndrome is not entirely understood.
Numerous experimental studies show that gut bacteria are influential in the development of obesity.
JMIR Res Protoc 2019;8(6):e11553
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In the last few years, nonalcoholic fatty liver disease (NAFLD) has gained attention, owing to its highest increase in the incidence among chronic liver diseases worldwide [3,4,7-9]. Some researchers consider NAFLD as a hepatic manifestation of metabolic syndrome, whereas others consider it a consequence of metabolic syndrome [3,10-13].
J Med Internet Res 2019;21(1):e11250
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