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Skip search results from other journals and go to results- 21 Journal of Medical Internet Research
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The study relies heavily on self-reported cardiovascular complications, which may introduce reporting bias. While a subset of cases was validated via medical records, the proportion of validated cases is not explicitly stated, and the possibility of underreporting or overreporting remains. The reliance on self-reported cardiovascular complications may have introduced reporting bias into the study.
JMIRx Med 2025;6:e79672
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Peer Review of “Cardiotoxicity in Pediatric Cancer Survivorship: Retrospective Cohort Study”
This significant and timely manuscript [1], which investigates the long-term cardiovascular complications in pediatric cancer survivors, has notable strengths, including its large cohort size, long-term follow-up, and utilization of a well-established dataset (Childhood Cancer Survivor Study). The methodology is generally sound, and the findings contribute meaningfully to our understanding of cardiotoxicity risks in childhood cancer survivors.
JMIRx Med 2025;6:e79523
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Peer Review of “Cardiotoxicity in Pediatric Cancer Survivorship: Retrospective Cohort Study”
cardiovascular
JMIRx Med 2025;6:e79521
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Cardiotoxicity in Pediatric Cancer Survivorship: Retrospective Cohort Study
Among these late effects, cardiovascular complications have emerged as a leading cause of morbidity and mortality in childhood cancer survivors [2].
Cardiotoxicity, a term encompassing a spectrum of cardiovascular adverse effects, can manifest in various forms including cardiomyopathy, coronary artery disease, valvular heart disease, and arrhythmias [3].
JMIRx Med 2025;6:e65299
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As a proof of concept, we apply our framework to predict cardiovascular disease (CVD) outcomes, myocardial infarction (MI), and stroke, among people with type 2 diabetes (T2 D). With CVD being a leading cause of death in the United States, and patients with T2 D being at elevated risk of CVD, it is urgent to develop accurate and fair predictive models that generate clinically reasonable predictions [16-19].
JMIR Med Inform 2025;13:e66200
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Cardiovascular diseases (CVDs), the leading cause of mortality globally, encompass a variety of disorders that impair the heart and blood vessels (eg, coronary heart disease, cerebrovascular disease, and peripheral arterial disease) [1,2]. In China, approximately 330 million individuals are afflicted with CVDs, constituting 46.9% of total annual deaths [3].
J Med Internet Res 2025;27:e66249
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Data pertaining to cerebrovascular and cardiovascular surgeries were visualized and analyzed using word clouds (Multimedia Appendix 2). For cerebrovascular surgery patients, the prominent keywords were “surgery,” “hospital,” “test,” “receive,” and “symptom.” For cardiovascular surgery patients, the key terms that emerged were “surgery,” “hospital,” “receive,” “eat,” “admission,” and “symptom.”
JMIR Med Inform 2025;13:e65127
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Women, racial and ethnic minorities, and people who reside in rural settings have historically been underrepresented in randomized clinical trials testing or evaluating interventions for cardiovascular diseases [2-6]. Causes of such underrepresentation are multifactorial and related to the individual or patient, investigator, and health care system factors [1,7,8].
JMIR Cardio 2025;9:e66436
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