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The Association of Macronutrient Consumption and BMI to Exhaled Carbon Dioxide in Lumen Users: Retrospective Real-World Study

The Association of Macronutrient Consumption and BMI to Exhaled Carbon Dioxide in Lumen Users: Retrospective Real-World Study

A variety of mobile health apps, including Lumen, which are designed for mobility and ubiquity, have demonstrated promising results in enhancing metabolism and facilitating weight management [19]. Using real-time data tracking, these tools empower individuals to make more informed health decisions [20]. As such, mobile apps such as Lumen have the potential to make a positive difference in people’s health and well-being [21].

Shlomo Yeshurun, Tomer Cramer, Daniel Souroujon, Merav Mor

JMIR Mhealth Uhealth 2024;12:e56083

Impact of Biological and Lifestyle Factors on Cognitive Aging and Work Ability in the Dortmund Vital Study: Protocol of an Interdisciplinary, Cross-sectional, and Longitudinal Study

Impact of Biological and Lifestyle Factors on Cognitive Aging and Work Ability in the Dortmund Vital Study: Protocol of an Interdisciplinary, Cross-sectional, and Longitudinal Study

The benefit of the Dortmund Vital Study will be that profound knowledge regarding the interactions among metabolism, the immune system, genetics, the brain structure and function, and cognition will be gained. In the long run, this knowledge will lead to empirically based intervention strategies to preserve cognitive functioning, work ability, and promote healthy cognitive aging.

Patrick D Gajewski, Stephan Getzmann, Peter Bröde, Michael Burke, Cristina Cadenas, Silvia Capellino, Maren Claus, Erhan Genç, Klaus Golka, Jan G Hengstler, Thomas Kleinsorge, Rosemarie Marchan, Michael A Nitsche, Jörg Reinders, Christoph van Thriel, Carsten Watzl, Edmund Wascher

JMIR Res Protoc 2022;11(3):e32352

Treatment of Barth Syndrome by Cardiolipin Manipulation (CARDIOMAN) With Bezafibrate: Protocol for a Randomized Placebo-Controlled Pilot Trial Conducted in the Nationally Commissioned Barth Syndrome Service

Treatment of Barth Syndrome by Cardiolipin Manipulation (CARDIOMAN) With Bezafibrate: Protocol for a Randomized Placebo-Controlled Pilot Trial Conducted in the Nationally Commissioned Barth Syndrome Service

The causative gene TAZ encodes the protein tafazzin, whose aberrant function perturbs the metabolism of the phospholipid cardiolipin (CL). CL is a major constituent of inner mitochondrial membranes and, therefore, majorly affects the muscular tissues that are most reliant on energy production. This results in infantile cardiomyopathy (including stillbirth) and lifelong severe exercise intolerance, lethargy, and fatigue [1].

Lucy Dabner, Guido E Pieles, Colin G Steward, Julian P Hamilton-Shield, Andrew R Ness, Chris A Rogers, Chiara Bucciarelli-Ducci, Rosemary Greenwood, Lucy Ellis, Karen Sheehan, Barnaby C Reeves

JMIR Res Protoc 2021;10(5):e22533

A Handheld Metabolic Device (Lumen) to Measure Fuel Utilization in Healthy Young Adults: Device Validation Study

A Handheld Metabolic Device (Lumen) to Measure Fuel Utilization in Healthy Young Adults: Device Validation Study

With increasing age, metabolism changes, as can be seen in various metabolic cart studies [18-20]. Future studies will need to examine whether RER metabolic cart levels correspond to Lumen CO2 levels in older subjects and those with metabolic conditions. Unlike the metabolic cart, the Lumen device does not measure oxygen consumption.

Kent Arnold Lorenz, Shlomo Yeshurun, Richard Aziz, Julissa Ortiz-Delatorre, James Robert Bagley, Merav Mor, Marialice Kern

Interact J Med Res 2021;10(2):e25371

The Feasibility of Examining the Effects of Gastric Bypass Surgery on Intestinal Metabolism: Prospective, Longitudinal Mechanistic Clinical Trial

The Feasibility of Examining the Effects of Gastric Bypass Surgery on Intestinal Metabolism: Prospective, Longitudinal Mechanistic Clinical Trial

The goal of biobanking is to allow future studies to test the hypothesis that the mechanism of action of RYGB involves specific changes in the postsurgical short- and long-term metabolism and morphology of the jejunum (Roux limb) [4]. Specifically, the intestine enhances its metabolism and activity after gastric bypass, resulting in an increase in fuel utilization.

Anita P Courcoulas, Margaret A Stefater, Eleanor Shirley, William F Gourash, Nicholas Stylopoulos

JMIR Res Protoc 2019;8(1):e12459