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Digital Biomarker–Based Interventions: Systematic Review of Systematic Reviews

Digital Biomarker–Based Interventions: Systematic Review of Systematic Reviews

DBMs are “objective, measurable, physiological, and behavioral parameters collected using wearable, portable, implantable, or digestible digital devices” [2]. In this research, we defined DBMs as either behavioral/physiological data or the digital devices used to collect these data. Wearable, implantable, or digestible medical devices or sensors that generate physiologic or behavioral data were considered digital biomarkers (eg, fitness trackers and defibrillators).

Hossein Motahari-Nezhad, Hana Al-Abdulkarim, Meriem Fgaier, Mohamed Mahdi Abid, Márta Péntek, László Gulácsi, Zsombor Zrubka

J Med Internet Res 2022;24(12):e41042

Digital Biomarker–Based Studies: Scoping Review of Systematic Reviews

Digital Biomarker–Based Studies: Scoping Review of Systematic Reviews

A new notion, digital biomarkers, has emerged in medicine: “objective, quantifiable, physiological and behavioral measures collected using digital devices that are portable, wearable, implantable or digestible” [4]. In addition to their clinical value, digital biomarkers enable new health care value chains [5].

Hossein Motahari-Nezhad, Meriem Fgaier, Mohamed Mahdi Abid, Márta Péntek, László Gulácsi, Zsombor Zrubka

JMIR Mhealth Uhealth 2022;10(10):e35722

Implantation of an Innovative Intracardiac Microcomputer System for Web-Based Real-Time Monitoring of Heart Failure: Usability and Patients’ Attitudes

Implantation of an Innovative Intracardiac Microcomputer System for Web-Based Real-Time Monitoring of Heart Failure: Usability and Patients’ Attitudes

In this context, the patients’ perspective on the use and acceptance of these innovative implantable technologies has been poorly studied. We here report our experience with implantation of a new intracardiac device designed to monitor the left intra-atrial pressure (LAP) of patients with chronic HF through an internet-based information system. The applicability and effectiveness of this technology are currently under evaluation in a multicenter prospective trial (V-LAP study).

Giuseppe D´Ancona, Monica Murero, Sebastian Feickert, Hilmi Kaplan, Alper Öner, Jasmin Ortak, Hueseyin Ince

JMIR Cardio 2021;5(1):e21055

Bioimpedance Alerts from Cardiovascular Implantable Electronic Devices: Observational Study of Diagnostic Relevance and Clinical Outcomes

Bioimpedance Alerts from Cardiovascular Implantable Electronic Devices: Observational Study of Diagnostic Relevance and Clinical Outcomes

Cardiac resynchronization therapy (CRT) devices and implantable cardioverter-defibrillators (ICDs) are guideline-recommended treatments for heart failure with reduced ejection fraction, left bundle branch block, very wide QRS complex (>150 ms), or sudden cardiac death [1,2]. The use of these cardiovascular implantable electronic devices (CIEDs) is rapidly increasing with 51,274 and 85,289 patients, respectively, receiving a CRT or ICD device in Europe in 2013 [3].

Christophe JP Jp Smeets, Julie Vranken, Jo Van der Auwera, Frederik H Verbrugge, Wilfried Mullens, Matthias Dupont, Lars Grieten, Hélène De Cannière, Dorien Lanssens, Thijs Vandenberk, Valerie Storms, Inge M Thijs, Pieter M Vandervoort

J Med Internet Res 2017;19(11):e393